SRBio Ultra-Potent Rumex Crispus Extract
Pharmaceutical-Grade Botanical for Metabolic, Hepatic & Dermatological Formulations
SRBio’s Extraction Excellence
Proprietary Technology
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Dual-Phase Extraction:
• Phase 1: Supercritical CO₂ extraction (40°C, 250 bar) isolates heat-sensitive anthraquinones (emodin, chrysophanol)
• Phase 2: Ethanol-water gradient extraction concentrates flavonoids (quercetin, luteolin)
→ Yields 20% higher bioactive retention vs. single-phase methods -
Nanofiltration Purification:
Removes tannins/proteins → Zero bitterness, 99.9% solvent-free (GC-MS validated)
Bioactive Standardization
| Compound | Concentration | Pharmacological Action |
|---|---|---|
| Emodin | 5-30% (custom) | ↓ Hepatic fibrosis (TGF-β1 inhibition) |
| Total Flavonoids | 15-40% (custom) | ↑ Insulin sensitivity (AMPK activation) |
| Chrysophanol | ≥1.2% | Anti-microbial (MRSA/MSSA inhibition) |
Clinically Validated Efficacy
Human Health Applications
✅ Liver Detoxification (In Vivo Data):
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200mg/day × 8 weeks:
• ↓ ALT/AST by 40-52% (alcohol-induced liver injury model)
• ↓ Collagen deposition by 32% (histopathology)
✅ Type 2 Diabetes Management (IC50 Values): -
α-Glucosidase inhibition: 0.78 mg/mL (vs. acarbose: 1.02 mg/mL)
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↓ Postprandial glucose by 28% (OGTT trial)
✅ Dermatological Repair (Clinical Observation): -
5% Serum Application:
• ↓ Acne lesions: 41% (8 weeks, n=45)
• ↑ Wound closure rate: 35% (MMP-9/TIMP-1 modulation)
Animal Nutrition Benefits
🐓 Broiler Chickens (0.1% Feed Additive):
• ↑ Villus height: 18% (jejunum histology)
• ↓ E. coli colonization: 3.2 log CFU/g (vs. control)
• ↓ Feed conversion ratio (FCR) by 11%
SRBio’s Unmatched Supply Chain
Vertical Integration
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Organic Farming:
200-hectare contract farms in Gansu (arid climate → 2× anthraquinone accumulation) -
In-House Labs:
HPLC-UV/ELISA for real-time potency tracking (ISO 17025 accredited) -
Export-Ready Packaging:
• 1-5kg: Double-aluminum foil bags (oxygen absorber)
• 25kg: Fiber drums with desiccant
Global Compliance
| Certification | Coverage | Test Method |
|---|---|---|
| FDA-GMP | Heavy metals (Pb<0.5ppm, Cd<0.2ppm) | ICP-MS |
| EU Organic | 482 pesticides undetected | QuEChERS LC-MS/MS |
| ISO 9001 | Microbials (TAMC<1000 CFU/g) | USP <61> |
| KOSHER/HALAL | Solvent residues (<1ppm ethanol) | GC-FID |
Technical Specifications
| Parameter | Specification | Test Report |
|---|---|---|
| Appearance | Fine brown powder | COA-2203 |
| Particle Size | 100% through 80 mesh | SOP-PS-008 |
| Loss on Drying | ≤5.0% | USP <731> |
| Ash Content | ≤8.0% | AOAC 942.05 |
| Emodin | 5.0-30.0% (adjustable) | HPLC-PDA |
| Total Flavonoids | 15.0-40.0% (adjustable) | UV-Vis 510nm |
Industry-Specific Solutions
Nutraceutical Formulators
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Liver Health Capsules:
250mg extract (std. 10% emodin) + milk thistle synergy -
Blood Sugar Control:
Microencapsulated powder for timed release (masking bitterness)
Cosmeceutical Developers
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Acne Serums:
5% extract + 2% zinc PCA (↓ C. acnes biofilm) -
Wound Healing Gel:
3% extract + hyaluronic acid (↑ fibroblast migration)
Animal Feed Manufacturers
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Antibiotic Alternative:
0.1% powder in premix (↓ necrotic enteritis in poultry)
Ordering & Logistics
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MOQ: 1kg (pilot batches), 10kg for custom standardization
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Lead Time:
• Stock items: 3 working days
• Custom potency: 10-15 days -
Global Shipping:
DHL Express (3 days USA), FOB Shanghai (incoterms 2020)
Quality Validation
Third-Party Studies
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Liver Protection:
Journal of Hepatology (2023): 32% ↓ collagen vs. silymarin (p<0.01) -
Stability:
24-month accelerated testing → Emodin degradation: 0.38%/year at 25°C
Client Success
“SRBio’s 20% emodin extract reduced our product development time by 6 months. Clinical results exceeded expectations.”
– Dr. Elena Rossi, Head R&D, EU
Partner Perks
🔬 Free Formulation Support:
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Compatibility studies with 50+ excipients
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Solubility/stability testing reports
📦 Private Label Services: -
Custom COAs with brand logo
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Dual-language packaging (EN/ES/FR)
⚡ Fast-Track Sampling:
Shipment within 24hrs (DDP terms available)
SRBio Advantage:
✓ 15 Years Botanical Expertise
✓ 47 Patents in Extraction Tech
✓ Zero QC Failures in EU/US Audits (2020-2024)
✓ 1,200+ B2B Clients in 52 Countries
Video & Articles
Xi’an SR Bio-Engineering Co., Ltd
Xi’an SRBio is a professional wholesale provider of many quality nutritional supplements products and AMINO ACID Powde etc.
We supply powder, tablets and capsules.
