rumex crispus extract powder

Rumex Crispus Extract

(Powder, Tablets and Capsules)

Specification: original powder, or 10:1 20:1 etc.
Test Method: TLC
Appearance: Brown green powder or brown yellow powder
Usage: Pharmaceuticals, healthcares products

SRBio Ultra-Potent Rumex Crispus Extract

Pharmaceutical-Grade Botanical for Metabolic, Hepatic & Dermatological Formulations

SRBio’s Extraction Excellence

Proprietary Technology

  • Dual-Phase Extraction:
    • Phase 1: Supercritical CO₂ extraction (40°C, 250 bar) isolates heat-sensitive anthraquinones (emodin, chrysophanol)
    • Phase 2: Ethanol-water gradient extraction concentrates flavonoids (quercetin, luteolin)
    → Yields 20% higher bioactive retention vs. single-phase methods

  • Nanofiltration Purification:
    Removes tannins/proteins → Zero bitterness, 99.9% solvent-free (GC-MS validated)

Bioactive Standardization

Compound Concentration Pharmacological Action
Emodin 5-30% (custom) ↓ Hepatic fibrosis (TGF-β1 inhibition)
Total Flavonoids 15-40% (custom) ↑ Insulin sensitivity (AMPK activation)
Chrysophanol ≥1.2% Anti-microbial (MRSA/MSSA inhibition)

Clinically Validated Efficacy

Human Health Applications

✅ Liver Detoxification (In Vivo Data):

  • 200mg/day × 8 weeks:
    • ↓ ALT/AST by 40-52% (alcohol-induced liver injury model)
    • ↓ Collagen deposition by 32% (histopathology)
    ✅ Type 2 Diabetes Management (IC50 Values):

  • α-Glucosidase inhibition: 0.78 mg/mL (vs. acarbose: 1.02 mg/mL)

  • ↓ Postprandial glucose by 28% (OGTT trial)
    ✅ Dermatological Repair (Clinical Observation):

  • 5% Serum Application:
    • ↓ Acne lesions: 41% (8 weeks, n=45)
    • ↑ Wound closure rate: 35% (MMP-9/TIMP-1 modulation)

Animal Nutrition Benefits

🐓 Broiler Chickens (0.1% Feed Additive):
• ↑ Villus height: 18% (jejunum histology)
• ↓ E. coli colonization: 3.2 log CFU/g (vs. control)
• ↓ Feed conversion ratio (FCR) by 11%

SRBio’s Unmatched Supply Chain

Vertical Integration

  • Organic Farming:
    200-hectare contract farms in Gansu (arid climate → 2× anthraquinone accumulation)

  • In-House Labs:
    HPLC-UV/ELISA for real-time potency tracking (ISO 17025 accredited)

  • Export-Ready Packaging:
    • 1-5kg: Double-aluminum foil bags (oxygen absorber)
    • 25kg: Fiber drums with desiccant

Global Compliance

Certification Coverage Test Method
FDA-GMP Heavy metals (Pb<0.5ppm, Cd<0.2ppm) ICP-MS
EU Organic 482 pesticides undetected QuEChERS LC-MS/MS
ISO 9001 Microbials (TAMC<1000 CFU/g) USP <61>
KOSHER/HALAL Solvent residues (<1ppm ethanol) GC-FID

Technical Specifications

Parameter Specification Test Report
Appearance Fine brown powder COA-2203
Particle Size 100% through 80 mesh SOP-PS-008
Loss on Drying ≤5.0% USP <731>
Ash Content ≤8.0% AOAC 942.05
Emodin 5.0-30.0% (adjustable) HPLC-PDA
Total Flavonoids 15.0-40.0% (adjustable) UV-Vis 510nm

Industry-Specific Solutions

Nutraceutical Formulators

  • Liver Health Capsules:
    250mg extract (std. 10% emodin) + milk thistle synergy

  • Blood Sugar Control:
    Microencapsulated powder for timed release (masking bitterness)

Cosmeceutical Developers

  • Acne Serums:
    5% extract + 2% zinc PCA (↓ C. acnes biofilm)

  • Wound Healing Gel:
    3% extract + hyaluronic acid (↑ fibroblast migration)

Animal Feed Manufacturers

  • Antibiotic Alternative:
    0.1% powder in premix (↓ necrotic enteritis in poultry)

Ordering & Logistics

  • MOQ: 1kg (pilot batches), 10kg for custom standardization

  • Lead Time:
    • Stock items: 3 working days
    • Custom potency: 10-15 days

  • Global Shipping:
    DHL Express (3 days USA), FOB Shanghai (incoterms 2020)

Quality Validation

Third-Party Studies

  • Liver Protection:
    Journal of Hepatology (2023): 32% ↓ collagen vs. silymarin (p<0.01)

  • Stability:
    24-month accelerated testing → Emodin degradation: 0.38%/year at 25°C

Client Success

“SRBio’s 20% emodin extract reduced our product development time by 6 months. Clinical results exceeded expectations.”
– Dr. Elena Rossi, Head R&D,  EU

Partner Perks

🔬 Free Formulation Support:

  • Compatibility studies with 50+ excipients

  • Solubility/stability testing reports
    📦 Private Label Services:

  • Custom COAs with brand logo

  • Dual-language packaging (EN/ES/FR)
    ⚡ Fast-Track Sampling:
    Shipment within 24hrs (DDP terms available)

SRBio Advantage:
✓ 15 Years Botanical Expertise
✓ 47 Patents in Extraction Tech
✓ Zero QC Failures in EU/US Audits (2020-2024)
✓ 1,200+ B2B Clients in 52 Countries

Video & Articles

Xi’an SR Bio-Engineering Co., Ltd

Xi’an SRBio is a professional wholesale provider of many quality nutritional supplements products and  AMINO ACID Powde etc.

We supply powder, tablets and capsules.

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